EVOS Research Roundup — W41 2026
A curated batch of independent peer-reviewed papers mentioning the EVOS M3000, EVOS M5000, EVOS M7000, EVOS S1000, CellInsight CX7 and EVOS Onstage Incubator imaging platforms. Each card is tagged by disease area and imaging technique and links to Google Scholar, PubMed and the original DOI.
Search source: Europe PMC / PubMed Central full-text index (2025–2026). Plankton & Zoom does not host paywalled content.
EVOS M7000
Myogenic dysregulation underlies human tongue overgrowth in Beckwith-Wiedemann syndrome.
iScience, 2026 — Developmental Biology / Muscle · Peer-reviewed journal
Macroglossia is a clinically significant feature of Beckwith-Wiedemann syndrome. Using pediatric tongue specimens and iPSC-derived myoblasts, the study shows BWS macroglossia is characterized by skeletal muscle fiber hypertrophy rather than increased fiber number, implicating myogenic dysregulation.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Structure- and Dynamics-Driven Discovery of Small Molecule Inhibitors Targeting a Conserved Pocket near the Fusion Peptide in the Prefusion SARS-CoV-2 S2 Glycoprotein Subunit.
ACS Omega, 2026 — Virology / Infectious Disease · Peer-reviewed journal
A structure- and dynamics-driven virtual screening identifies small-molecule inhibitors of SARS-CoV-2 cell entry by targeting a conserved pocket within the prefusion S2 subunit, with antiviral activity validated in cell-culture assays.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Mimicking tumor hypoxia in a glioblastoma-on-a-chip.
Materials Today Bio, 2026 — Cancer / Organ-on-a-Chip · Peer-reviewed journal
This study presents a microfluidic glioblastoma-on-a-chip that recreates the hypoxic tumor microenvironment, enabling evaluation of oxygen gradients, cell viability, and drug response in patient-derived GBM cells.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Assessing microglial phagocytosis of apoptotic neurons in vitro: a multimodal approach.
Frontiers in Neuroscience, 2026 — Neuroscience / Glia · Peer-reviewed journal
Microglial phagocytosis of apoptotic neurons is assessed with a multimodal workflow combining live-cell imaging, flow cytometry, and immunofluorescence, relevant to neurodegenerative diseases such as Alzheimer's and glaucoma.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Gfpt2 modulates fibroblast activation by glutathione metabolism.
Journal of Molecular and Cellular Cardiology, 2026 — Cardiac Fibrosis / Metabolism · Peer-reviewed journal
Fibroblast activation during tissue fibrosis involves metabolic reprogramming. This work identifies Gfpt2 as a glutathione-metabolism regulator that modulates fibroblast activation, with implications for fibrotic heart disease.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
EVOS M5000
Berberine Chloride Suppresses Growth of Canine Osteosarcoma Cells via Regulating MMP2/AKT/β-Catenin Pathway.
Antioxidants, 2026 — Veterinary Oncology / Cell Signaling · Peer-reviewed journal
Canine osteosarcoma shares biological features with human osteosarcoma. Berberine chloride is shown to suppress osteosarcoma cell growth by modulating MMP2, AKT, and β-catenin signaling, supporting its adjuvant potential.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Construction and Characterization of Paired Patient-Derived Cell Models for Solitary Fibrous Tumors (SFTs).
Cancers, 2026 — Cancer / Rare Tumor Models · Peer-reviewed journal
Paired patient-derived cell models of solitary fibrous tumors are established and characterized, providing a preclinical platform for understanding SFT biology and testing candidate therapeutics.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
A genetically encoded sensor of ionic stress links cellular proton dynamics to sleep.
Science Advances, 2026 — Neuroscience / Biosensors · Peer-reviewed journal
A genetically encoded nuclear translocation ionic sensor (GENTIS) enables direct visualization of ionic stress in vivo. Longitudinal imaging reveals links between cellular proton dynamics and sleep/wake states.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Inflammasome activation dictates the efficacy of antimycobacterial activity of frontline TB drugs.
PLOS Pathogens, 2026 — Infectious Disease / Immunology · Peer-reviewed journal
Host-directed therapy may improve tuberculosis treatment. This study shows that inflammasome activation status influences the antimycobacterial efficacy of frontline TB drugs, highlighting a host-pathogen interaction target.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Targeting Bruton tyrosine kinase with acalabrutinib attenuates murine sclerodermatous chronic graft versus host disease.
Frontiers in Immunology, 2026 — Transplant Immunology / Fibrosis · Peer-reviewed journal
Chronic graft-versus-host disease involves B-cell and T-cell driven inflammation and fibrosis. Acalabrutinib, a Bruton tyrosine kinase inhibitor, attenuates sclerodermatous cGVHD in a murine model.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
EVOS M3000
Spheroid cultures reveal cancer stem cell enrichment and distinct chemotherapeutic response in triple-negative breast cancer.
BMC Cancer, 2026 — Cancer / 3D Culture · Peer-reviewed journal
Three-dimensional spheroid cultures of triple-negative breast cancer cell lines reveal cancer stem cell enrichment and subtype-specific drug responses, demonstrating the value of 3D models in preclinical testing.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Precision tumor-on-chip for personalized assessment of drug efficacy and immune cell delivery.
Cell Reports Methods, 2026 — Cancer / Microfluidics · Peer-reviewed journal
A microfluidic tumor-on-chip integrates patient-derived organoids with a functional endothelial barrier and liquid flow, enabling personalized assessment of drug efficacy and immune-cell delivery into tumor tissue.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Plant- and Algae-Derived Compounds Enhance the Anticancer Activity of Doxorubicin in Colorectal Cancer Cell Lines.
Molecules, 2026 — Cancer / Natural Products · Peer-reviewed journal
Natural products from marine algae and plants are evaluated as adjuvants to doxorubicin in colorectal cancer cell lines, showing modulation of apoptosis, oxidative stress, and proliferation pathways.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Selective vulnerability of cerebral vasculature to NOTCH3 variants in small vessel disease and rescue by phosphodiesterase-5 inhibitor.
Science Advances, 2026 — Neuroscience / Vascular Biology · Peer-reviewed journal
NOTCH3 variants cause CADASIL, the most common monogenic small-vessel disease. This study identifies selective vulnerability of cerebral vasculature to NOTCH3 mutations and explores phosphodiesterase-5 inhibition as a rescue strategy.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial Autophagy.
Cellular and Molecular Neurobiology, 2026 — Neuroscience / BBB · Peer-reviewed journal
Cardiac arrest causes blood-brain barrier injury via ischemia-reperfusion. The nitric oxide-releasing prodrug JS-K protects brain endothelial cells by inhibiting HMGB1-ATG5 mediated autophagy.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
EVOS S1000
Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT.
Nature Communications, 2026 — Cancer / Spatial Proteomics · Peer-reviewed journal
INSIGHT combines intravital imaging and spatial proteomics to dissect signaling networks in disseminated glioblastoma cells in vivo, revealing therapeutic vulnerabilities in invasive tumor cell populations.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Spatial T lymphocyte infiltration into the primary melanoma tumor associates with survival.
Melanoma Research, 2026 — Cancer / Spatial Immunity · Peer-reviewed journal
Multiplex whole-slide immunofluorescence is used to quantify spatial T-lymphocyte infiltration in primary melanoma, showing that objective spatial metrics of immune infiltration associate with patient survival.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Amygdala-liver signalling orchestrates glycaemic responses to stress.
Nature, 2025 — Neuroscience / Metabolism · Peer-reviewed journal
Behavioural adaptations to environmental threats depend on rapid glucose mobilization. This work identifies an amygdala-liver signaling axis that orchestrates glycaemic responses to acute stress in mice.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
CellInsight CX7
Intravenously deliverable oncolytic virus VET3-TGI favorably alters the tumor microenvironment.
Journal for ImmunoTherapy of Cancer, 2026 — Cancer Immunotherapy / Oncology · Peer-reviewed journal
Oncolytic viruses can prime anti-tumor immunity, but intravenous delivery remains challenging. VET3-TGI is engineered for systemic delivery and shown to favorably reshape the tumor microenvironment and anti-tumor immune responses.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
From in silico prediction to experimental validation: Identification of drugs and novel synergistic combinations that inhibit growth of inflammatory breast cancer cells.
PLOS One, 2026 — Cancer / Drug Repurposing · Peer-reviewed journal
Drug repurposing candidates for inflammatory breast cancer, identified by computational approaches, are experimentally validated in cell-based assays, revealing synergistic drug combinations that inhibit IBC cell growth.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Cholesterol dysregulation in APOE4 astrocytes promotes α-synuclein pathology in miBrains.
Cell Stem Cell, 2026 — Neuroscience / iPSC Models · Peer-reviewed journal
An iPSC-derived 3D brain model (miBrain) is used to show that APOE4 astrocytes exhibit cholesterol dysregulation that promotes α-synuclein aggregation, linking lipid metabolism to synucleinopathy.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Dynamic neuro-immune regulation of psychiatric risk loci in human neurons.
Nature Communications, 2026 — Neuroscience / Psychiatric Genomics · Peer-reviewed journal
Maternal and fetal immune activation interact with polygenic psychiatric risk in human neurons. Allele-specific regulatory mapping reveals dynamic neuro-immune regulation of psychiatric risk loci.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
ALY688 Protects Against Myocardial Ischemia-Reperfusion Injury via Direct Effects and Rab8a-Dependent Extracellular Vesicles.
Journal of Extracellular Vesicles, 2026 — Cardiovascular / Extracellular Vesicles · Peer-reviewed journal
ALY688, an adiponectin receptor agonist peptide, protects the heart against ischemia-reperfusion injury through direct cardiomyocyte effects and Rab8a-dependent extracellular-vesicle signaling.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
EVOS Onstage Incubator
Modeling maternal immune activation in 3D ex vivo human fetal brain cerebroids reveals IL-17A-driven disruption of cortical development.
Nature Neuroscience, 2026 — Neurodevelopment / Organoids · Peer-reviewed journal
Three-dimensional ex vivo human fetal brain cerebroids preserve cortical architecture and are used to model maternal immune activation, showing IL-17A-driven disruption of cortical development.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Construction and Characterization of Paired Patient-Derived Cell Models for Solitary Fibrous Tumors (SFTs).
Cancers, 2026 — Cancer / Rare Tumor Models · Peer-reviewed journal
Paired patient-derived cell models of solitary fibrous tumors are established and characterized, providing a preclinical platform for SFT biology and drug-response studies under controlled culture conditions.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut-on-a-Chip.
Advanced Science, 2026 — Tissue Engineering / Fibrosis · Peer-reviewed journal
A physiodynamic human gut-on-a-chip model demonstrates that fluid shear stress and mechanical strain guide intestinal fibroblast fate and profibrotic remodeling, mimicking early fibrotic disease processes.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids.
Nature Communications, 2025 — Infectious Disease / Organoids · Peer-reviewed journal
Human neural organoids exposed to a clade IIb monkeypox virus isolate reveal cell-to-cell viral spread and neuronal death, providing insights into the neurological complications of MPXV infection.
Google Scholar | PubMed | DOI / Full Text
Frequently asked questions about this study
Which platform was used in this research? The paper summary identifies the EVOS as the imaging or high-content screening platform used in this study.
Why is this paper relevant to EVOS users? It shows a real experimental workflow run on the EVOS, demonstrating the kind of quantitative, reproducible data the platform can produce in a UK research lab.
Frequently asked questions
How are papers selected?
We search Europe PMC / PubMed Central full-text indices for exact model names, restrict results to 2025–2026 publications, verify the microscope is named in the article text, and link to Google Scholar, PubMed and the publisher DOI.
Can these protocols be reproduced on other microscopes?
Yes, most brightfield, fluorescence and live-cell assays are transferable to any inverted fluorescence microscope with compatible objectives and filters.
Last updated: 2026-10-07 by Plankton & Zoom.