Live Cell Microscope UK: EVOS M5000 Roundup W29

A curated batch of independent peer-reviewed papers mentioning the EVOS M5000 Imaging System. Each card is tagged by disease area, cell type and imaging technique and links to Google Scholar, PubMed/PMC and the original DOI.

Ultrasound-Generated Nanoscale Mechanical Stimulation to Regulate Stem Cell Differentiation.

2026 ACS nanoscience Au — Stem Cells and Regenerative Medicine

Harnessing nanoscale mechanical cues to direct stem cell fate represents a transformative strategy in cell-engineered tissue regeneration. In this study, we demonstrate that low-frequency ultrasound (LFU) induces nanoscale vertical displacements (30-65 nm) at…

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Lenvatinib Suppresses Colorectal Cancer Cell Growth, Migration, and Invasion

2026 In vivo (Athens, Greece) — Cell Biology

Colorectal cancer (CRC) remains a major cause of cancer mortality. Lenvatinib, a multi-kinase inhibitor, has emerging anticancer potential, but its effects in CRC are not fully defined. The aim of this study was to identify potential treatment mechanism and…

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Benzydamine rescues ethanol-induced teratogenesis in zebrafish FASD model.

2025 Scientific reports — Infectious and Immunology

Fetal alcohol spectrum disorders (FASD) are a group of physical, behavioral, and cognitive impairments caused by ethanol exposure during pregnancy. Zebrafish have emerged as a useful model for researching FASD and its variants in recent years. Oxidative…

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The c-Myc/TBX3 Axis Promotes Cellular Transformation of Sarcoma-Initiating Cells.

2021 Frontiers in oncology — Cancer

Sarcomas are highly aggressive cancers of mesenchymal origin whose clinical management is highly complex. This is partly due to a lack of understanding of the molecular mechanisms underpinning the transformation of mesenchymal stromal/stem cells (MSCs) which…

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In Vivo and In Vitro Expression of iC1, a Methylation-Controlled J Protein (MCJ) in Bovine Liver, and Response to In Vitro Bovine Fatty Liver Disease Model.

2023 Animals : an open access journal from MDPI — Tissue and Disease Models

Mitochondrial complex I inhibitor (iC1) is a methylation-controlled J protein (MCJ) that decreases cellular respiration by inhibiting oxidative phosphorylation. Recent rodent studies showed that loss or inhibition of iC1 was associated with preventing lipid…

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Morphological and Molecular Characterization of Apple Scab (

2025 Current issues in molecular biology — Skin and Biomaterials

Apple scab, caused by the fungus

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<i>Mentha rotundifolia</i>, a Source of Amoebicidal Agents Against <i>Naegleria fowleri</i>.

2025 International journal of molecular sciences — Imaging Methods

Current therapies for Primary Amoebic Meningoencephalitis (PAM) present several limitations; consequently, there is an urgent need to develop new therapeutic agents. In this regard, we undertook bioassay-guided isolation of

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Graphene oxide-microplastic hybrid showcase elicited discrepancy through intrinsic interaction mediated steatosis, and apoptosis in macrophages.

2026 Materials today. Bio — Toxicology and Environmental

The widespread natural abundance of microplastics (MP) has been recognized to pose significant global health concerns, particularly due to limited understanding of their biological interactions. With the uncontrolled increase in MP accumulation in the…

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Protocol for extraction and characterization of mouse brain-derived extracellular matrix for neuronal cell culture.

2025 STAR protocols — Neuroscience

Neuronal cell cultures are highly sensitive to their microenvironment, particularly the choice of coating substrate. Here, we present a protocol to isolate extracellular matrix (ECM) from mouse brain tissue, providing a native coating material that closely…

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Filovirus infection disrupts epithelial barrier function and ion transport in human iPSC-derived gut organoids.

2025 PLoS pathogens — Infectious and Immunology

Gastrointestinal (GI) dysfunction, characterized by severe diarrhea and dehydration, is a central contributor to morbidity and mortality in filovirus disease in patients, yet the role of the epithelium in this clinical outcome remains poorly defined. Here, we…

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Integrated In Silico and In Vitro Study of Copper Nanocatalyzed Carbonyl-Functionalized Triazoles-Inducing S Phase Cell Cycle Arrest and Apoptosis in MCF-7.

2026 ChemistryOpen — Cell Biology

The demand for novel, selective anticancer agents, driven by drug resistance and systemic toxicity of current treatments, underscores the importance of targeted drug discovery. Present research involved cytotoxic screening of a series of synthesized copper…

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Antagonistic Mechanisms of Probiotic Aliivibrio sp. Strain Vl2 Against Moritella viscosa: Evidence from Co-cultivation and Targeted Transcriptomic Analysis.

2026 Probiotics and antimicrobial proteins — Infectious and Immunology

Winter ulcers, primarily caused by Moritella viscosa, represent a significant challenge for the Norwegian aquaculture industry. Effective control measures are hampered by the lack of effective vaccines and limited use of antibiotics, driven by the global…

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Recent Publications

Boutros et al. (2015)

Microscopy-based high-content screening. Cell 163:1312–1314. doi:10.1016/j.cell.2015.11.025

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Zbinden et al. (2020)

A confluence-based automated image analysis pipeline for high-throughput screening. PLoS ONE 15:e0229298. doi:10.1371/journal.pone.0229298

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What is a research roundup?

A curated summary of recent publications and trends around a microscopy application.