A curated batch of independent peer-reviewed papers mentioning the CellInsight CX7 High-Content Screening Platform. Each card is tagged by disease area, cell type and imaging technique and links to Google Scholar, PubMed/PMC and the original DOI.
2026 Research square — Cancer
Increasing threats of viral disease underscore the urgent need for broad-spectrum antiviral drugs (BSADs). Host proteins utilized by human pathogenic viruses are key BSAD targets. The vacuolar-type H+-ATPase (V-ATPase) has been identified as a proviral factor for most pH-dependent enveloped viruses classified as pandem...
Google Scholar | PubMed | DOI
2026 Cancer cell international — Cancer
BACKGROUND: Ovarian cancer (OC) is the most lethal of gynecological cancers and presents a poor prognosis due to difficulty in early diagnosis, extensive abdominal metastasis and chemo-resistance. We utilized single-cell transcriptomics to deconvolute intratumoral heterogeneity and identify biomarkers and therapeutic t...
Google Scholar | PubMed | DOI
2026 Autophagy — Cancer
The term CASM describes a process in which MAP1LC3B/LC3B and other Atg8-family proteins are covalently ligated to lipids in damaged endomembranes. While CASM is commonly described as a cytoprotective response to multiple types of membrane damage, how CASM helps cells maintain homeostasis is still unclear. Here, we show...
Google Scholar | PubMed | DOI
2026 PloS one — High-Content Screening
Infection with human immunodeficiency virus (HIV-1) remains a global health issue and still drives the development of significant pathology and various comorbidities. Antiretroviral therapy (ART) can effectively suppress viral replication but is often initiated months or years after initial infection, leaving a substan...
Google Scholar | PubMed | DOI
2026 Emerging microbes & infections — High-Content Screening
Human TMPRSS2 is a type II transmembrane serine protease and an essential host factor for SARS-CoV-2 and influenza A virus (IAV H1N1) infections. It facilitates the cleavage of viral surface glycoproteins, which are required for membrane fusion. This importance makes it an attractive target for host-directed antiviral ...
Google Scholar | PubMed | DOI
2026 ACS omega — High-Content Screening
Drug repurposing, in principle, can speed antiviral drug discovery. Among the molecules most frequently advanced in such repurposing efforts is a group of structurally diverse cationic amphiphilic drugs (CADs). While CADs have shown micromolar to mid-nanomolar antiviral activity in cell-based assays, they can induce ph...
Google Scholar | PubMed | DOI
2026 Research square — Infectious Disease & Neuroscience
BRD1 is an epigenetic regulator implicated in neurodevelopmental and psychiatric disorders, yet its role in human neuronal differentiation, maturation, and function remains poorly understood. Here we show that BRD1 haploinsufficiency disrupts early neuronal programming, resulting in accelerated maturation and altered n...
Google Scholar | PubMed | DOI
2026 JACC. Basic to translational science — Infectious Disease & Neuroscience
Pediatric cardiomyopathy is a major cause of diastolic heart failure; yet, its mechanisms remain unclear. Global myocardial transcriptomic and blood lipidomic profiling revealed a distinct metabolic signature of diastolic dysfunction marked by dysregulated lipid signaling. A machine learning model using these gene mark...
Google Scholar | PubMed | DOI
2026 Stem cell reports — Infectious Disease & Neuroscience
Altered microglial lipid metabolism is heavily implicated in Alzheimer's disease (AD) and aging. Recently, protocols were developed to generate human induced pluripotent stem cell-derived microglia-like cells (iMGL) to study microglial function in vitro, including embryoid body-based methods and induced transcription f...
Google Scholar | PubMed | DOI
Explore more CellInsight CX7 literature: Cancer | High-Content Screening | Infectious Disease & Neuroscience | Research Index
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Molecular Biology of the Cell, 7th ed. W.W. Norton. doi:10.1201/9781003217356
View on DOINIH Image to ImageJ: 25 years of image analysis. Nature Methods 9:671–675. doi:10.1038/nmeth.2089
View on DOIPractical UK-focused microscopy advice, product comparisons and application-specific tips for researchers.
Brightfield, phase contrast and fluorescence imaging of cells, tissues and 3D models in research labs.
Yes, most protocols are transferable to any inverted fluorescence microscope with the right objectives and filters.