EVOS Research Roundup — W37 2026

A curated batch of independent peer-reviewed papers mentioning the EVOS M3000, EVOS M5000, EVOS M7000, EVOS S1000, CellInsight CX7 and EVOS Onstage Incubator imaging platforms. Each card is tagged by disease area and imaging technique and links to Google Scholar, PubMed/PMC and the original DOI.

Search source: Europe PMC / PubMed Central full-text index (2025–2026). Plankton & Zoom does not host paywalled content.

EVOS M5000

Ginsenosides Rb3 and Rc Exhibit Anti-Amoebic Activities Against <i>Naegleria fowleri</i>, the Etiological Agent of Primary Amoebic Meningoencephalitis.

— Infectious Disease / Parasitology · Peer-reviewed journal, 2026

Background/Objectives: Naegleria fowleri is an opportunistic pathogen causing primary amoebic meningoencephalitis (PAM), a fatal neuroinflammatory disease with a high mortality rate of over 97%, in humans. Currently, there are no approved therapeutics for PAM, underscoring the...

Google Scholar | PubMed | DOI / Full Text

Lipid transfer proteins and PI4KIIα initiate nuclear p53-phosphoinositide signaling.

— Cell Biology / Cancer · Peer-reviewed journal, 2026

Phosphoinositide (PIP n ) messengers are present in non-membranous regions of nuclei where they are assembled into a phosphatidylinositol (PI) 3-kinase (PI3K)/Akt pathway that is distinct from the cytosolic membrane-localized pathway. In one nuclear pathway, PI kinases/phospha...

Google Scholar | PubMed | DOI / Full Text

Conserved pathogenesis of ancestral and contemporary Oropouche virus strains in a murine pregnancy model.

— Infectious Disease / Virology · Peer-reviewed journal, 2026

Oropouche virus (OROV) is an emerging orthobunyavirus responsible for widespread outbreaks across South and Central America. Recent reports of congenital disease have raised urgent concerns regarding the potential risk of OROV infection during pregnancy. Here, we establish an ...

Google Scholar | PubMed | DOI / Full Text

Phenolic-Rich Extracts from Artichoke By-Products Promote Apoptosis in Human Colorectal Cancer Cell Lines.

— Cancer / Nutrition · Peer-reviewed journal, 2026

Background: Apoptosis is a fundamental process for maintaining tissue homeostasis, and its dysregulation is closely linked to the development of numerous diseases, including colorectal cancer. In recent years, dietary polyphenols have gained interest due to their antioxidant, ...

Google Scholar | PubMed | DOI / Full Text

EVOS M7000

JQKD82 Inhibits HIV Infection of Macrophages Through Blocking Viral Entry and Enhancing Antiviral ISG Responses.

— Infectious Disease / HIV · Peer-reviewed journal, 2026

JQKD82 is an epigenetic modulator that inhibits lysine-specific demethylase 5 (KDM5), a host factor implicated in HIV latency and cell survival. Although JQKD82 has been studied in latent HIV infection of T cell models, its effects on HIV infection in macrophages remain unclea...

Google Scholar | PubMed | DOI / Full Text

Diosgenin Alleviates Age-Related Sarcopenia by Promoting Satellite Cell Proliferation and Myogenic Differentiation via Activation of the SIRT1/PGC-1α Signaling Pathway.

— Aging / Muscle · Peer-reviewed journal, 2026

Age-related sarcopenia is characterized by a progressive decline in skeletal muscle mass and function, with satellite cell dysfunction representing a central pathogenic mechanism. Diosgenin, a steroidal saponin derived from plants of the Dioscorea genus, has demonstrated poten...

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Collagen hybridizing peptide imaging and delivery of therapeutic antibody in rheumatoid arthritis models.

— Immunology / Rheumatoid Arthritis · Peer-reviewed journal, 2026

The use of immunosuppressive therapies for rheumatoid arthritis (RA) is associated with substantial adverse effects. In addition, existing diagnostic reagents are limited in their ability to detect local joint damage. Here, we address both these needs using a collagen-hybridiz...

Google Scholar | PubMed | DOI / Full Text

Proteasome Targeting with Carfilzomib Induces Reactive Oxygen Species-Mediated Apoptosis in Hepatoblastoma.

— Cancer / Proteasome · Peer-reviewed journal, 2026

Hepatoblastoma (HB) is the most common malignant liver tumor in children, yet therapeutic options remain largely confined to conventional chemotherapy. To identify novel therapeutic targets, we performed gene set enrichment analysis on three publicly available HB datasets and ...

Google Scholar | PubMed | DOI / Full Text

EVOS M3000

Plant- and Algae-Derived Compounds Enhance the Anticancer Activity of Doxorubicin in Colorectal Cancer Cell Lines.

— Cancer / Colorectal · Peer-reviewed journal, 2026

Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, and the efficacy of conventional chemotherapy is frequently limited by systemic toxicity, chemoresistance, and tumor recurrence. Natural products derived from marine algae and plan...

Google Scholar | PubMed | DOI / Full Text

Nitric Oxide Donor Alleviates Cardiac Arrest Induced Blood Brain Barrier Injury by Inhibiting HMGB1-ATG5 Mediated Endothelial Autophagy.

— Neuroscience / BBB · Peer-reviewed journal, 2026

Cardiac arrest (CA) and subsequent cardiopulmonary resuscitation (CPR) often cause severe neurological deficits due to ischemia–reperfusion (I/R) injury, marked by systemic inflammation, blood–brain barrier (BBB) dysfunction, and excessive autophagy. JS-K, a nitric oxide-relea...

Google Scholar | PubMed | DOI / Full Text

Selective vulnerability of cerebral vasculature to <i>NOTCH3</i> variants in small vessel disease and rescue by phosphodiesterase-5 inhibitor.

— Neuroscience / Cerebral Vasculature · Peer-reviewed journal, 2026

NOTCH3 variants cause CADASIL (cerebral autosomal dominant arteriopathy and subcortical infarcts and leukoencephalopathy), the most common monogenetic form of small vessel disease (SVD) and vascular dementia (VaD). The molecular mechanisms driving CADASIL pathogenesis remain p...

Google Scholar | PubMed | DOI / Full Text

EVOS S1000

Mapping Immunity With Cutting-Edge Spatial Biology and Tissue Cytometry Innovations.

— Immunology / Spatial Biology · Peer-reviewed journal, 2026

The immune system operates within organized tissue landscapes, where spatial relationships between cells shape the nature and outcome of immune responses. Over the past decade, protein imaging-based spatial technologies have transformed how immune responses are studied within ...

Google Scholar | PubMed | DOI / Full Text

Amygdala-liver signalling orchestrates glycaemic responses to stress.

— Neuroscience / Metabolism · Peer-reviewed journal, 2025

Behavioural adaptations to environmental threats are crucial for survival 1,2 and necessitate rapid deployment of energy reserves 3-5 . The amygdala coordinates behavioural adaptations to threats 6 , but little is known about its involvement in underpinning metabolic adaptatio...

Google Scholar | PubMed | DOI / Full Text

CellInsight CX7

Evaluation of a human 3D multicellular hepatic spheroid model as a platform for studying hepatic transporters.

— Hepatology / Organoids · Peer-reviewed journal, 2025

There is growing demand for improved in vitro liver models to better predict in vivo pharmacology, specifically drug disposition mediated by hepatic transporters and assessment of transporter-mediated drug interaction risk. While 2D sandwich-cultured human hepatocytes (SCHH) r...

Google Scholar | PubMed | DOI / Full Text

Modeling immune responses of cattle to <i>Mycobacterium bovis</i> using magnetic bioprinted granulomas.

— Infectious Disease / Tuberculosis · Peer-reviewed journal, 2025

Tuberculosis (TB) remains a threat for human and livestock health. Mycobacteria causing TB are host-adapted pathogens that occasionally spill over into other species. Mycobacterium bovis causes bovine TB, a well-known zoonosis. Mycobacterium tuberculosis is adapted to humans a...

Google Scholar | PubMed | DOI / Full Text

Mapping spatial organization of in vitro neuronal networks using high-content imaging.

— Neuroscience / High-Content · Peer-reviewed journal, 2025

Neuronal network formation is an intricate process by which individual neurons connect into a functional circuitry. At the subcellular level, neuronal connectivity is characterized by the number, size and strength of synapses. At the cellular level, in vitro network characteri...

Google Scholar | PubMed | DOI / Full Text

EVOS Onstage Incubator

Endothelial Features Along the Pulmonary Vascular Tree in Chronic Thromboembolic Pulmonary Hypertension: Distinctive or Shared Facets?

— Pulmonary / Cardiovascular · Peer-reviewed journal, 2025

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of pulmonary embolism, characterized by the presence of organized fibro-thrombotic material that partially or fully obstructs the lumen of large pulmonary arteries, microvasculopathy, and enlargement ...

Google Scholar | PubMed | DOI / Full Text

Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids.

— Infectious Disease / Neuroscience · Peer-reviewed journal, 2025

In 2022-23, the world witnessed the largest recorded outbreak of monkeypox virus (MPXV). Neurological manifestations were reported alongside the detection of MPXV DNA and MPXV-specific antibodies in the cerebrospinal fluid of patients. Here, we analyze the susceptibility of ne...

Google Scholar | PubMed | DOI / Full Text

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Frequently Asked Questions

What does this roundup cover?

UK-focused, independent curation of recently indexed peer-reviewed papers that name EVOS or CellInsight microscope systems in their methods.

How are papers selected?

We search Europe PMC / PubMed Central full-text indices for exact model names, restrict results to 2025–2026 publications, verify the microscope is named in the article text, and link to Google Scholar, PubMed and the publisher DOI.

Can these protocols be reproduced on other microscopes?

Yes, most brightfield, fluorescence and live-cell assays are transferable to any inverted fluorescence microscope with compatible objectives and filters.

Last updated: 2026-09-09 by Plankton & Zoom.