A curated batch of independent peer-reviewed papers mentioning the EVOS M5000 Imaging System. Each card is tagged by disease area, cell type and imaging technique and links to Google Scholar, PubMed/PMC and the original DOI.
— Cancer
In the nucleus, chromosomes are hierarchically folded into active (A) and inactive (B) compartments composed of topologically associating domains (TADs). Genomic regions interact with nuclear lamina, termed lamina-associated domains (LADs). However, the molecular mechanisms under...
Google Scholar | PubMed | DOI
— Cancer
BACKGROUND: MYCN amplification is a prognostic biomarker associated with poor prognosis of neuroblastoma in children. The overall survival of children with MYCN-amplified neuroblastoma has only marginally improved within the last 20 years. The Bromodomain and Extra-Terminal motif...
Google Scholar | PubMed | DOI
— Cancer
Long noncoding RNAs (lncRNAs) have been demonstrated to play significant roles in non-small cell lung cancer (NSCLC) progression. Recently, a newly identified lncRNA, LncRNA LINC00668 (LINC00668), was reported to be involved in the regulation of progression of several tumors. How...
Google Scholar | PubMed | DOI
— Cell Biology & Signaling
Proteins can function as biomarkers of pathological conditions, such as neurodegenerative diseases, infections or metabolic syndromes. Engineering cells to sense and respond to these biomarkers may help the understanding of molecular mechanisms underlying pathologies, as well as ...
Google Scholar | PubMed | DOI
— Cell Biology & Signaling
R-spondins (RSPOs) amplify WNT signaling during development and regenerative responses. We previously demonstrated that RSPOs 2 and 3 potentiate WNT/β-catenin signaling in cells lacking leucine-rich repeat-containing G-protein coupled receptors (LGRs) 4, 5 and 6 (Lebensohn and Ro...
Google Scholar | PubMed | DOI
— Cell Biology & Signaling
Nuclear speckles (NS) are among the most prominent biomolecular condensates. Despite their prevalence, research on the function of NS is virtually restricted to colocalization analyses, since an organizing core, without which NS cannot form, remains unidentified. The monoclonal a...
Google Scholar | PubMed | DOI
— Infectious Disease & Immunology
The B cell adaptor protein (BCAP) is a multimodular regulator of inflammatory signaling in diverse immune system cells. BCAP couples TLR signaling to phosphoinositide metabolism and inhibits MyD88-directed signal transduction. BCAP is recruited to the TLR signalosome forming mult...
Google Scholar | PubMed | DOI
— Infectious Disease & Immunology
Viral pandemics, such as the one caused by SARS-CoV-2, pose an imminent threat to humanity. Because of its recent emergence, there is a paucity of information regarding viral behavior and host response following SARS-CoV-2 infection. Here we offer an in-depth analysis of the tran...
Google Scholar | PubMed | DOI
— Infectious Disease & Immunology
COVID-19 has spread worldwide since 2019 and is now a severe threat to public health. We previously identified the causative agent as a novel SARS-related coronavirus (SARS-CoV-2) that uses human angiotensin-converting enzyme 2 (hACE2) as the entry receptor. Here, we successfully...
Google Scholar | PubMed | DOI
Explore more EVOS M5000 literature: Cancer | Cell Biology & Signaling | Infectious & Immunology | Research Index
Considering an M5000 for your UK lab? Read the EVOS M5000 review or compare it with the EVOS M3000 vs M5000 UK comparison.
Molecular Biology of the Cell, 7th ed. W.W. Norton. doi:10.1201/9781003217356
View on DOINIH Image to ImageJ: 25 years of image analysis. Nature Methods 9:671–675. doi:10.1038/nmeth.2089
View on DOIPractical UK-focused microscopy advice, product comparisons and application-specific tips for researchers.
Brightfield, phase contrast and fluorescence imaging of cells, tissues and 3D models in research labs.
Yes, most protocols are transferable to any inverted fluorescence microscope with the right objectives and filters.